The Ducho group works on novel antibiotics derived from antibiotically active natural products. A particular focus is set on nucleoside antibiotics which inhibit an early intracellular step of bacterial cell wall biosynthesis. The biosynthesis of such natural products is also investigated. Another research project deals with the synthesis and investigation of modified nucleic acid structures for fundamental research and biomedical applications.
The English version of the internet pages of the Ducho group at the University of Paderborn is still under construction and will soon be launched.
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