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Soft matter
Prof. Dr. Klaus Huber
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Targeted Synthesis of the Type-A Particle Substructure from Enzymatically Produced Eumelanin
A. Büngeler, F. Kollmann, K. Huber, and O. I. Strube
Biomacromolecules (2022) 23, 3, 1020-1029 DOI:

Spatial Distribution of Intracellular Ion Concentrations in Aggregate-Forming HeLa Cells Analyzed by μ-XRF Imaging
A. Gräfenstein, C. Rumancev, R. Pollak, B. Hämisch, V. Galbierz, W. H. Schroeder, J. Garrevoet, G. Falkenberg, T. Vöpel, K. Huber, S. Ebbinghaus, and A. Rosenhahn
ChemistryOpen (2022) 11, e2022000 DOI:


Thermodynamic Analysis of the Self-Assembly of Pseudo Isocyanine Chloride in the Presence of Crowding Agents
B. Hämisch, R. Pollak, S. Ebbinghaus, and K. Huber
ChemSystemsChem. (2021) 3, e2000051 DOI:

Multiresponsive Polymer Nanoparticles Based on Disulfide Bonds
M. Wagner, A. Krieger, M. Minameyer, B. Hämisch, K. Huber,
T. Drewello, and F. Gröhn

Macromolecules (2021), 54, 6, 2899–2911 DOI:

Mechanism and equilibrium thermodynamics of H- and J-aggregate formation from pseudo isocyanine chloride in water
B. Hämisch, and K. Huber
Soft Matter (2021), 17(35), 8140-8152 DOI:

Self-Assembled Fibrinogen Hydro- and Aerogels with Fibrin-like 3D Structures
D. Hense, A. Büngeler, F. Kollmann, M. Hanke, A. Orive, A. Keller, G. Grundmeier, K. Huber, and O. I. Strube
Biomacromolecules (2021), 22, 10, 4084-4094 DOI:


Contrast variation of micelles composed of Ca2+ and blockcopolymers of two negatively charged polyelectrolytes
N. Carl, S. Prévost, R. Schweins and K. Huber
Colloid. Polym. Sci. (2020) 298 (7) 663-679 DOI: org/10.1007/s00396-019-04596-1

Self-Assembly of Pseudo-Isocyanine Choride as a Sensor for Macromolecular Crowding In Vitro and In Vivo
B. Hämisch, R. Pollak, S. Ebbinghaus and K. Huber
Chem. Eur. J. (2020) 26 (31), 7041-7050 DOI: 10.1001/chem.202000113

The Molecular Mechanism of Polymer Formation of Farnesylated Human Guanylate-binding Protein 1
L. Sistemich, M. Kutsch, B. Hämisch, P. Zhang, S. Shydlovskyi, N. Britzen-Laurent, M. Stürzl, K. Huber and C. Herrmann
J. Mol. Biol. (2020) 432 (7), 2164−2185

Controlling Self-Assembly with Light and Temperature
N. Carl, W. Müller, R. Schweins and K. Huber
Langmuir (2929) 36, 223-231 DOI: 10.1021/acs.langmuir.9b03040


On Protein Folding in Crowded Conditions
D. Gomez, K. Huber and S. Klumpp
J. Phys. Chem. Lett (2019) 10, 7650-7656 DOI: 10.1021/acs.jpclett.9b02642

Invertible Micelles Based on Ion-Specific Interactions of Sr2+ and Ba2+ with Double Anionic Block Copolyelectrolytes
N. Carl, S. Prévost, R. Schweins, J. Houston, I. Morfin and K. Huber
Macromolecules (2019) 52 (22), 8759-8770 DOI: 10.1021/acs.macromol.9b01924

Phase Transformation Behavior of Polylactide Probed by Small Angle Light Scattering and Calorimetry
N. Schmidt, S. Keuker-Baumann, J. Meyer and K. Huber
J. Polymer. Sci., Part B: Polym. Physics (2019) 57 (22), 1483-1495 DOI: 10.1002/polb.24892

Ion-selective binding as a new trigger for micellization of block copolyelectrolytes with two anionic blocks
N. Carl, S. Prévost, R. Schweins and K. Huber
Soft Matter (2019) 15 (41), 8266 - 8271 DOI: 10.1039/C9SM01138B

Self-Assembly of Fibrinogen in Aequos, Thrombin-Free Solutions of Variable Ionic Strenghts
B. Hämisch, A. Büngeler, C. Kielar, A. Keller, O. Strube and K. Huber
Langmuir (2019) 35 (37), 12113-12122 DOI: 10.1021/acs.langmuir.9b01515


Effect of ionic strength on the structure and elongational kinetcs of vimentin filaments
C. Lopez, O. Saldanha, A. Aufderhorst-Roberts, C. Martinez-Torres, M. Kuijs, G. H. Koenderink, S. Köster and K, Huber
Soft Matter (2018) 14, 8445-8454 DOI: 10.1039/c8sm01007b

Secondary Particle Formation during the Nonaqueous Synthesis of Metal Oxide Nanocrystals
P. Stolzenburg, B. Hämisch, S. Richter, K. Huber and G. Garnweitner
Langmuir (2018) 34 (43), 12834-12844 DOI:10.1021/acs.langmuir.8b00020

Insight into Fast Nucleation and Growth of Zeolitic Imidazolate Framework-71 by In Situ Static Light Scattering at Variable Temperature and Kinetic Modeling
S. Saha, M. Wiebcke and K. Huber
Cryst. Growth Des. (2018) 18 (8), pp 4653-4661 DOI: 10.1021/acs.cgd.8b00626

Polyacrylates in the Presence of an Extraordinary Monovalent Cation - Solution Behavior and Metal Nanoparticle Formation
A. Urbanski, M. Hansch, C. G. Lopez, R. Schweins, Y Hertle, T. Hellweg, F. Polzer and K. Huber
The Journal of Chemical Physics (2018) 149 (11), 163318 DOI: 10.1063/1.5028182

Reaction enthalpy from the binding of multivalent cations to anionic poylelectrolytes in dilute solutions
M. Hansch, H. P. Kaub, S. Deck, N. Carl and K. Huber
The Journal of Chemical Physics (2018) 148 (11), 114906 DOI: 10.1063/1.5019877

Liquid-liquid phase separation in dilute solutions of poly(styrene sulfonate) with multivalent cations: Phase diagrams, chain morphology, and impact of temperature
M. Hansch, B. Hämisch, R. Schweins, S. Prévost and K. Huber
The Journal of Chemical Physics (2018) 148 (1), 014901  DOI: 10.1063/1.5006618


Silica Polymerization from Supersaturated Dilute Aqueous Solutions in the Presence of Alkaline Earth Salts
M. Kley, A. Kempter, V. Boyko and K. Huber
Langmuir (2017) 33 (24), 6071-6083; DOI:10.1021/acs.langmuir.7b00887 

Insight into the Final Step of the Supramolecular Buildup of Eumelanin
A. Büngeler, B. Hämisch, K. Huber, W. Bremser and O. I. Strube
Langmuir (2017) 33 (27), 6895-6901; DOI:10.1021/acs.langmuir.7b01634


Lateral association and elongation of vimentin intermediate filament proteins: A time-resolved light-scattering study

C. G. Lopez, O. Saldanha, K. Huber and S. Köster
PNAS (2016) 113, 11152-11157; DOI:10.1073/pnas.1606372113

Contraction and Coagulation of Spherical Polyelectrolyte Brushes in the Presence of Ag+, Mg2+, and Ca2+ Cations

A. Ezhova and K.Huber
Macromolecules (2016) 49, 7460-7468; DOI: 10.1021/acs.macromol.6b01286

Insight into Fast Nucleation and Growth of Zeolitic Imidazolate Framework-71 by In Situ Time-Resolved Light and X-ray Scattering Experiments

S. Saha, S. Springer, M. E. Schweinefuß, D. Pontoni, M. Wiebcke and K. Huber
Cryst.Growth&Des. (2016), 16 (4), 2002-2010

Systematic Limitations in Concentration Analysis via Anomalous Small-Angle X-ray Scattering in the Small Structure Limit

G. Goerigk, S. Lages and K. Huber
Polymers (2016) 8, 85

Metastable metal imidazolates: development of target syntheses by combining experimental and theoretical investigations of the Formation mechanism

C. A. Schröder, S. Sha, K. Huber, S. Leoni and M. Wiebke
Zeitschrift für Kristallographie - Crystalline Materials (2014) 229, 807-822

Specific Interactions of Ag+ Ions with Anionic Polyacrylate Chains in Dilute Solution

A. Ezhova and K. Huber
Macromolecules (2014) 47, 8002-8011

Mechanistic Studies of Silica Polymerization from Supersaturated Aqueous Solutions by means of Time-Resolved Light Scattering

M. Kley, A. Kempter, V. Boyko and K. Huber
Langmuir (2014) 30, 12664−12674

Conformation and Interactions of Polystyrene and Fullerenes in Dilute to Semidilute Solutions
R. Dattani, R. Michels, A. J. Nedoma, R. Schweins, P. Westacott, K. Huber and J. T. Cabral
Macromolecules (2014) 47, 6113–6120

Monitoring the Coordination Modulator Shell at MOF Nanocrystals
D. Zacher, R. Nayuk, R. Schweins, R. A. Fischer and K. Huber
Cryst.Growth&Des. (2014), 14, 4859−4863

Coaggregation of Two Anionic Azo Dyestuffs: A Combined Static Light Scattering and Small-Angle X-ray Scattering Study
R. Michels, G. Goerigk, U. Vaino, J. Gummel and K. Huber
J. Phys. Chem. B (2014), 118, 7618–7629

Zeolitic imidazolate framework-71 nanocrystals and a novel SOD-type polymorph: solution mediated phase transformations, phase selection via coordination modulation and a density functional theory derived energy landscape
M. E. Schweinefuß, S. Springer, I. A. Baburin, T. Hikov, K. Huber, S. Leoni and M. Wiebcke
Dalton Transactions (2014), 43, 3528-3536


Morphology of Blends with Cross-Linked PMMA Microgels and Linear PMMA Chains
M. Schneider, R. Michels, V. Pipich, G. Goerigk, V. Sauer, H.-P. Heim and K. Huber
Macromolecules (2013), 46, 9091-9103

Kinetic and Structural Features of a Dyestuff Co-Aggregation Studied by Time-Resolved Static Light Scattering
R. Michels, Y. Hertle, T. Hellweg and K. Huber
J. Phys. Chem. B (2013), 117, 15165-15175

Co-Aggregation of Two Anionic Azo Dyestuffs at a Well-Defined Stoichiometry

R. Michels, T. Sinemus, J. Hoffmann, B. Brutschy and K. Huber
J. Phys. Chem. B (2013) 117, 8611-8619

SAXS and ASAXS on Dilute Sodium Polyacrylate Chains Decorated with Lead Ions
S. Lages, G. Goerigk and K. Huber
Macromolcules (2013) 46 (9), 3570-3580


Formfactors of Hollow and Massive Rectangular Parallelepipeds at Variable Degree of Anisometry
R. Nayuk and K. Huber
Z. Phys. Chem. (2012) 226, 837-854

Modulated Formation of MO-5 nanoparticles - A SANS Analysis
R. Nayuk, D. Zacher, R. Schweins, C. Wiktor, R. A. Fischer, G. van Tendeloo and K. Huber
J. Phys. Chem. C (2012) 116(10), 6127-6135

Upper Critical Solution Temperature of Poly(N-acryloyl glycinamide) in Water: A Concealed Property
J. Seuring, F. M. Bayer, K. Huber and S. Agarwal
Macromolecules (2012) 45, 374–384

Impact of Sodium Polyacrylate on the Amorphous Calcium Carbonate Formation from Supersaturated Solution
J. Liu, S. Pancera, V. Boyko, J. Gummel, R. Nayuk and K. Huber
Langmuir (2012) 28, 3593-3605

In-situ static and dynamic light scattering and scanning electron microscopy study on the crystallization of the dense zinc imidazolate framework ZIF-zni
T. Hikov, C. A. Schröder, J. Cravillon, M. Wiebcke and K. Huber
Phys. Chem. Chem. Phys. (2012) 14, 511-521


Molecular Recognition with 2,4-Diaminotriazine Functionalized Colloids
F. M. Bayer, M. Tang, R. Michels, C. Schmidt and K. Huber
Langmuir (2011) 27, 12851-12858

Fast Nucleation and growth of ZIF-8 Nanocrystals monitored by Time-Resolved Wide-Angle and Small Angle X-Ray scattering
J. Cravillon, Ch. A. Schröder, R. Nayuk, J. Gummel, K. Huber and M. Wiebcke
Angewandte Chemie Int. Ed. (2011) 50, 8067-8071

Controlling Zeolitic Imidazolate Framework ano- and Microcrystal Formation: Inight into Crysal Growth by Time-Resolved In Situ Static Light Scattering
J. Cravillon, R. Nayuk, S. Springer S, A. Feldhoff, K. Huber and M. Wiebcke
Chemistry of Materials (2011) 2, 8130-2141

Self-localization of polyacrylic acid molecules on polar ZnO(0001)-Zn surfaces
C. Kunze, M. Valtiner, R. Michels, K. Huber and G. Grundmeier
Physical chemistry chemical physics PCCP (2011) 13, 12959-67


Evaluation of the Particle Growth of Amorphous Calcium Carbonate in Water by means of the Porod Invariant from SAXS

J. Liu, S. Pancera, V. Boyko, A. Shukla, T. Narayanan and Huber, K.
Langmuir (2010) 26, 17405–17412

Hydrogen-Bond-Induced Heteroassembly in Binary Colloidal Systems
F. M. Bayer, K. Hiltrop, and K. Huber
Langmuir (2010) 26, 13815–13822

Coil-collpase and Coil-Aggregation due to the Interaction of Cu2+ and Ca2+ Ions with Anionic Polyacrylate Chains in Dilute Solution
S. Lages, R. Michels and K. Huber
Macromolecules (2010) 43, 3027-3035

Formation of Ca2+-Induced Intermediate Necklace Structures of Polyacrylate Chains

S. Lages, P. Lindner, P. Sinha, A. Kiriy, M. Stamm and K. Huber
Macromolecules (2009) 42, 4288–4299

Rapid Room-Temperature Synthesis and Characterization of Nanocrystals of a Prototypical Zeolitic Imidazolate Framework

J. Cravillon, S. Münzer, S.-J. Lohmeyer, A. Feldhoff, K. Huber and M. Wiebcke 
Chemistry of Materials (2009) 21, 1410-1412

Nanocrystals of [Cu3(btc)2] (HKUST-1): A Combined Time Resolved Light Scattering and Scanning Electron Microscopy Study

D. Zacher, J. Liu, K. Huber and R. Fischer
Chemical Communications (2009) 1031-1033

Analysis of the Nucleation and Growth of Amorphous CaCO3 by Means of Time-Resolved Static Light Scattering

J. Liu, J. Rieger and K. Huber
Langmuir (2008), 24, 8262-8271 

Probing the extent of Sr2+ ion condensation to anionic polyacrylate coils: A quantitative anomalous small angle x-ray scattering study
G. Goerigk, K. Huber and R. Schweins
Journal of Chemical Physics (2007) 127, 154908

Temperature induced Collapse of Alkaline Earth Cation – Polyacrylate Anion Complexes

S. Lages, R. Schweins and  K. Huber
Journal of Physical Chemistry (2006) 111, 10431

Structure-Property Relationship in Stimulus-Responsive Bolaamphiphile Hydrogels;

A. Meister, M. Bastrop, S. Koschoreck, V. M. Garamus, T. Sinemus, G. Hempel, S. Drescher, B. Dobner, W. Richtering, K. Huber and A. Blume
Langmuir (2007), 23, 7715

Trapping Metal-Organic Framework Nanocrystals: An in-Situ Time-Resolveld Light Scattering Study on the Crystal Growth MOF-5 in Solution

S. Hermes, T. Witte, T. Hikov, D. Zacher, S. Bahnmüller, G. Langstein, K. Huber and R. A. Fischer
Journal of the American Chemical Society (2007) 129, 5324

Controlled Formation of Ag-Nanoparticles by Means of Long Chain Sodium Polyacrylates in Dilute


K. Huber, T. Witte, J. Hollmann and S. Keuker-Baumann
Journal of the American Chemical Society (2007) 129, 1089

Time Resolved Structure Analysis of Growing beta-Amyloid Fibers

T. Witte, L. A. Haller, E. Luttmann, J. Krüger, G. Fels and K. Huber
Journal of Structural Biology (2006) 159, 71

Specific Interactions between Anionic Polyacrylate Chains and Ca2+, Sr2+ and Ba2+ Ions

R. Schweins, G. Goerigk and K. Huber
The Europ.Phys.J. E-Soft Matter (2006) 21, 99-110 

Coil dimensions of Polystyrene Chains in Colloid-Polymer Mixtures at the Protein-Limit: A SANS Study

T. Kramer, R. Schweins and K. Huber
Macromolecules (2005) 38, 9783

Tribute to Walther Burchard

K. Huber M. Schmidt and W. Richtering
Macromolecules (2005) 38, 5358

Small-Angle Neutron Scattering of dilute Polystyrene Chains at the Protein Limit of a Colloid-Polymer Mixture

T. Kramer, R. Schweins and K. Huber 
Journal of Chemical Physics (2005) 123, 014903

Silsesquioxane Molecules and Polystyrene Chains as a Model System for Colloid-Polymer Mixtures in the Protein-Limit

T. Kramer, R. Schweins and K. Huber
Macromolecules (2005) 38, 151

Surface Modification of Epoxy-Functionalized Acrylate Colloids

T. Kramer, R. Röder, K. Huber and H.-S. Kitzerow
Polymers for Advanced Technologies (2005) 16, 38

Colloid-Polymer Mixtures in Solution with Refractive Index Matched Acrylate Colloids

T. Kramer, S. Scholz, M. Maskos and K. Huber
J. Coll.I nterf. Sci. (2004) 279, 44

Formation of Branched Calixarene-Aggregates – A Time Resolved Static Light Scattering


T. Witte, B. Decker, J. Mattay and K. Huber
J. Am. Chem. Soc. (2004) 126
, 9276

The Distribution of Sr2+-Counter ions around Polyacrylate Chains Analyzed by Anaomalous Small Angle X-Ray Scattering

G. Goerigk, R. Schweins, K. Huber and M. Ballauff
Europhys. Lett. (2003) 66, 331

Preparation of Positively and Negatively Charged Organic Colloids from a Single Precursor

T. Röder, T. Kramer, K. Huber and H.-S. Kitzerow
Macromolecular Chemistry and Physics (2003) 204, 2204

Calcium induced Shrinking of NaPA Chains – a SANS Investigation of Single Chain Behaviour

R. Schweins, P. Lindner and K. Huber
Macromolecules (2003) 36, 9564

Dilute Solution Behaviour of Sodium Polyacrylate Chains in Aqueous NaCl Solutions

R. Schweins, J. Hollmann and K. Huber
Polymer (2003) 44, 7131 

Particle Scattering Factor of Pearl Necklace Chains

R. Schweins and K. Huber
Macromolecular Symposia, (2004) 211, 25

Aggregation of Pseudoisocynine Chloride in Aqueous NaCl Solution
B. Herzog, K. Huber and H. Stegemeyer
Langmuir, (2003) 19, 5223

A Model of Polydisperse Wormlike Stars and its Application to Dyestuff Aggregates

A. Katzenstein and K. Huber
Langmuir, (2002) 18, 7049

Shift of Photonic Band Gap Material in two Phtonic Crystal/liquid crystal composites

G. Mertens, T. Röder, R. Schweins, K. Huber and H.S. Kitzerow
Applied Physics Letters (2002), 80, 1885   

Collapse of Sodium Polyacrylate Chains in Calcium Salt Solutions

R. Schweins and K. Huber
The Europ. Phys. J. E-Soft Matter (2001) 5, 117

A comparative experimental study of the aggregation of Acid Red 266 in aqueous solution by 

use of 19F-NMR, UV/Vis spectroscopy and static light scattering

B. Neumann, K. Huber and P. Pollmann
Phys.Chem.Chem.Phys. (2000) 2, 3687

Time Resolved Recording of Ionic Dyestuff Aggregation by Static Ligh Scattering
S. Escudero-Ingles, A. Katzenstein, W. Schlenker and K. Huber
Langmuir, (2000) 16, 3010

Ca2+ and Cu2+ Induced Conformational Changes of Sodium Polymethacrylate in Dilute

Aqueous Solution

Y. Ikeda, M. Beer, M. Schmidt and K. Huber
Macromolecules (1998) 31, 728

Mixtures of Polyacrylic Acid and Nonionic Surfactants at the Air-Water Interface
C. Maloney and K. Huber
J. Coll. Interf. Sci. (1994) 164, 463

Characterization of Wormlike Micelles Containing Solubilized Dye-Molecules by Light Scattering

B. Herzog, K. Huber and A. R. Rennie
J. Coll. Interf.Sci. (1994) 164, 370

Calcium-Induced Shrinking of Polyacrylate Chains in Aqueous Solution

K. Huber
J.Phys.Chem. (1993) 97 9825

Interactions in Mixed Interfaces of Binary Surfactant Solutions

K. Huber
J.Coll.Interf.Sci. (1991) 147, 321

Quasi-elastic Scattering by Semiflexible Rings

K. Huber, W. H. Stockmayer and K. Soda
Polymer (1990) 31, 1811

Scattering Behavior of Wormlike Star Macromolecules

K. Huber and W. Burchard
Macromolecules (1989) 22, 3332

Block Copolymers with Rigid and Flexible Segments

K. Huber
Macromolecules (1989) 22, 2750

Static and Dynamic Scattering from Block - Copolymeric Ring Molecules

K. Huber
Macromolecules (1988) 21, 1305

First cumulant of the dynamic structure factor for rigid rings

K. Huber and W. H. Stockmayer
Polymer (1987) 28, 1987

Osmotic Second Virial Coefficient and Two-Parameter Theories

K. Huber and W. H. Stockmayer
Macromolecules (1987) 20, 1400

Monte Carlo calculations in comparison to neutron scattering studies: 3. On the structure of 12-arm star molecules
K. Huber, W. Burchard, S. Bantle and L. J. Fetters
Polymer (1987) 28, 1997

Monte Carlo calculations in comparison to neutron scattering studies: 2. Global dimensions of 12-arm stars

K. Huber, W. Burchard, S. Bantle and L. J. Fetters
Polymer (1987) 28, 1990

Monte Carlo calculations in comparison to neutron scattering studies: 1. Linear chains

K. Huber, W. Burchard and S. Bantle
Polymer (1987) 28, 863

Semidilute Solutions of Star Branched Polystyrene: A Light and Neutron Scattering Study

K. Huber, S. Bantle, W. Burchard and L. J. Fetters  
Macromolecules (1986) 19, 1404 

Remarks on A2, Hydrodynamic Coil Expansion, and Concentration Dependence of the Diffusion Coefficient for Polystyrene in Toluene

K. Huber, W. Burchard and Z. A. Akcasu
Macromolecules (1985) 18, 2743

Hydrodynamic and Thermodynamic Behavior of Short-Chain Polystyrene in Toluene and Cyclohexane at 34.5 °C

K. Huber, S. Bantle, P. Lutz and W. Burchard
Macromolecules (1985) 18, 1461:

Dynamic Light Scattering from Regular Star-Branched Molecules

K. Huber, W. Burchard and L. J. Fetters
Macromolecules (1984) 17, 541
Review articles

New experiments for the quantification of counterion condensation
K. Huber and U. Scheler
COCIS (2012) 17, 64-73

Conformation and Phase Diagramms of Flexible Polyelectolytes
Polyelectrolytes with defined Molecular Architecture,

N. Volk, D. Vollmer, M. Schmidt, W. Oppermann and K. Huber
Advances in Polymer Science, (Springer Verlag, 2003), 166, 29

Theory of Macromolecular Rings
W. Burchard and K. Huber
Semlyen, J. A. (Ed.), Large Ring Molecules,
John Wiley & Sons, Chichester (1996)


Schleroglucans and cosmetic compositions containing them
T. Maier,  K. Huber, U. Rau and B. Schilling

Enzyme activity enhancement by addition of an (hetero)aromatic compound
I. J. Fletcher, K. Huber, R. Zink and B. Freiermuth

3,7-Diamino-fluoran compounds and thermoreactive recording Systems
W. Mischler and K. Huber

Mixture of colour Formers
R. Zink and K. Huber

Bleaching aids
A. Stehlin, K. Huber and T. Maier

Concentrated aqueous liquid formulations of color Formers
R. Scartazzini and K. Huber
EP0591106, B1;


Dr. rer. nat., Dipl. Chem. Klaus Huber

Physical Chemistry - Research Group Huber

group manager

Klaus Huber
+49 5251 60-2125
+49 5251 60-4208

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